Synthesis, antimalarial activity and cytotoxicity of substituted 3,6-diphenyl-[1,2,4,5]tetraoxanes

Identification of an antimalarial synthetic trioxolane drug development candidate

Jonathan L. Vennerstrom, Sarah Arbe‐Barnes, Reto Brun et al. · Nature · 2004 · 617 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Measurement of the Lactate Dehydrogenase Activity of Plasmodium falciparum as an Assessment of Parasitemia

Michael T. Makler, David J. Hinrichs · American Journal of Tropical Medicine and Hygiene · 1993 · 563 citations

Life Sciences, Biochemistry, Infectious Diseases +17

From Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New Chemistry

Richard K. Haynes, Simone C. Vonwiller · Accounts of Chemical Research · 1997 · 217 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides

Jonathan L. Vennerstrom, William Y. Ellis, Arba L. Ager et al. · Journal of Medicinal Chemistry · 1992 · 164 citations

Pharmacy, Chemistry, Pharmacology +8

Iodine as a Catalyst for Efficient Conversion of Ketones to <i>g</i><i>em</i>-Dihydroperoxides by Aqueous Hydrogen Peroxide

Katja Žmitek, Marko Zupan, Stojan Stavber et al. · Organic Letters · 2006 · 146 citations

Natural Sciences, Chemistry, Catalysis +9