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Reduction in Myocardial Collagen Cross-Linking Parallels Left Ventricular Dilatation in Rat Models of Systolic Chamber Dysfunction

Angela J. Woodiwiss, Oupa J. Tsotetsi, S. Sprott, Eric Lancaster, Theofanie Mela, Eugene S. Chung, Theo E. Meyer, Gavin R. Norton

Circulation · 2001 · 207 citations · 20 references

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Abstract

Because decreases in the ratio of myocardial insoluble to soluble collagen parallel LV dilatation in rats, reductions in myocardial collagen cross-linking may be an important mechanism contributing to LV dilatation in heart disease.

References

20

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