Concepedia

Short Synthesis of Cytotoxic 4‐Arylcoumarins

Eleonora Rizzi, Sabrina Dallavalle, Lucio Merlini, Graziella Pratesi, Franco Zunino

Synthetic Communications · 2006 · 20 citations · 12 references

DOI

Concepts

Abstract

Abstract A short synthesis of cytotoxic 4‐arylcoumarins via condensation of phenols with cinnamic acids in the presence of CF3COOH, followed by dehydrogenation with DDQ, is described.

References

12

Trifluoroacetic Acid-Mediated Hydroarylation:  Synthesis of Dihydrocoumarins and Dihydroquinolones

Kelin Li, Lindsay N. Hayes, Jon A. Tunge · The Journal of Organic Chemistry · 2005 · 133 citations

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Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins. Part 2

Sébastien Combes, Pascale Barbier, Soazig Douillard et al. · Journal of Medicinal Chemistry · 2011 · 127 citations

, , +9

Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins

Christian Bailly, Christine Bal, Pascale Barbier et al. · Journal of Medicinal Chemistry · 2003 · 123 citations

, , +14

Trifluoroacetic Acid Mediated Hydroarylation: Synthesis of Dihydrocoumarins and Dihydroquinolones.

Kelin Li, Lindsay N. Foresee, Jon A. Tunge · ChemInform · 2005 · 110 citations · Full text

, , +6

Demethylation of Methyl Aryl Ethers using Pyridine Hydrochloride in Solvent-free Conditions under Microwave Irradiation

Pramod Kulkarni, A. J. Kadam, R. B. Mane et al. · Journal of Chemical Research Synopses · 1999 · 36 citations

, , +7