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Differentially Expressed Androgen-Regulated Genes in Androgen-Sensitive Tissues Reveal Potential Biomarkers of Early Prostate Cancer

Dogus Murat Altintas, Nathalie Allioli, Myriam Decaussin, Simon de Bernard, A. Ruffion, Jacques Samarut, Virginie Vlaeminck‐Guillem

PLoS ONE · 2013 · 38 citations · 34 references

DOIFull text

Open access

Abstract

We identified ARG with reduced expression in PCa and with significant diagnostic values for discriminating between cancerous and non-cancerous prostatic tissues, similar that of PCA3. Given their expression pattern, they could be considered as potentially protective against prostate cancer. Moreover, they could be complementary to known genes overexpressed in PCa and included along with them in multiplex diagnostic tools.

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