Identification and Characterization of a Novel Class of c-Jun N-terminal Kinase Inhibitors

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Brydon L. Bennett, Dennis T. Sasaki, Brion W. Murray et al. · Proceedings of the National Academy of Sciences · 2001 · 2.6K citations · Full text

Life Sciences, Immunology, Pharmacology +17

A quantitative analysis of kinase inhibitor selectivity

Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

A small molecule–kinase interaction map for clinical kinase inhibitors

Miles A. Fabian, William Biggs, Daniel K. Treiber et al. · Nature Biotechnology · 2005 · 1.9K citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +12

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Masahiko Hibi, Anning Lin, Tod Smeal et al. · Genes & Development · 1993 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Cathy Tournier, Patricia Hess, Derek Yang et al. · Science · 2000 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +17