Concepedia

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

Chan Young Park, Paul Hoover, Franklin M. Mullins, Priti Bachhawat, Elizabeth D. Covington, Stefan Raunser, Thomas Walz, K. Christopher García, Ricardo E. Dolmetsch, Richard S. Lewis

Cell · 2009 · 954 citations · 34 references

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34

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

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STIM1, an essential and conserved component of store-operated Ca2 <b>+</b> channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin et al. · The Journal of Cell Biology · 2005 · 1.8K citations · Full text

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Shenyuan L. Zhang, Ying Yu, Jack Roos et al. · Nature · 2005 · 1.4K citations · Full text

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Orai1 is an essential pore subunit of the CRAC channel

Murali Prakriya, Stefan Feske, Yousang Gwack et al. · Nature · 2006 · 1.3K citations

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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

Andriy V. Yeromin, Shenyuan L. Zhang, Weihua Jiang et al. · Nature · 2006 · 804 citations · Full text

, , +16