Concepedia

Methylation of NEUROG1 in Serum Is a Sensitive Marker for the Detection of Early Colorectal Cancer

Andreas Herbst, Konstanze Rahmig, P Stieber, Alexander Philipp, Andreas Jung, Andrea Ofner, Alexander Crispin, Jens Neumann, R. Lamerz, Frank T. Kolligs

The American Journal of Gastroenterology · 2011 · 121 citations · 28 references

DOI

Abstract

Methylation of the NEUROG1 gene is frequently found in sera of patients with colorectal cancers independent of tumor stage. The quantitative detection of NEUROG1 DNA methylation in serum is a suitable approach for the non-invasive screening for asymptomatic colorectal cancer.

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