Concepedia

3-Substituted Pyrazole Analogs of the Cannabinoid Type 1 (CB1) Receptor Antagonist Rimonabant: Cannabinoid Agonist-Like Effects in Mice via Non-CB1, Non-CB2 Mechanism

Jenny L. Wiley, Dana E. Selley, Pinglang Wang, Rudresha Kottani, Srinivas Gadthula, Anu Mahadeven

Journal of Pharmacology and Experimental Therapeutics · 2011 · 17 citations · 34 references

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Concepts

References

34

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

, , +15

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

Murielle Rinaldi‐Carmona, Francis Barth, Michel Héaulme et al. · FEBS Letters · 1994 · 1.8K citations · Full text

, , +14

Identification and Functional Characterization of Brainstem Cannabinoid CB<sub>2</sub>Receptors

Marja D. Van Sickle, Marnie Duncan, Philip J. Kingsley et al. · Science · 2005 · 1.5K citations

, , +16

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

Andreas Zimmer, Anne Zimmer, Andrea G. Hohmann et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

, , +9