Concepedia

Expression of the chemokine receptor CXCR3 in human renal allografts—a prospective study

Ute Hoffmann, Stephan Segerer, Petra Rümmele, Bernd Krüger, Miriam Pietrzyk, Ferdinand Hofstädter, Bernhard Banas, Bernhard K. Krämer

Nephrology Dialysis Transplantation · 2006 · 36 citations · 25 references

DOIFull text

Open access

Abstract

A significant part of both CD4- and CD8-positive T cells express the chemokine receptor CXCR3. During renal allograft rejection, the number of these cells increases significantly at the site of injury and might be targeted by CXCR3 blocking agents.

References

25

The Banff 97 working classification of renal allograft pathology

Lorraine C. Racusen, Kim Solez, Robert B. Colvin et al. · Kidney International · 1999 · 3K citations

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions.

Suofu Qin, James B. Rottman, Patricia N. Myers et al. · Journal of Clinical Investigation · 1998 · 1.4K citations · Full text

, , +21

Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection

Wayne W. Hancock, Bao Lu, Wei Gao et al. · The Journal of Experimental Medicine · 2000 · 616 citations · Full text

Donor-Derived Ip-10 Initiates Development of Acute Allograft Rejection

Wayne W. Hancock, Wei Gao, Vilmos Csizmadia et al. · The Journal of Experimental Medicine · 2001 · 375 citations · Full text

, , +18

Expression of chemokines and chemokine receptors during human renal transplant rejection

Stephan Segerer, Yan Cui, Frank Eitner et al. · American Journal of Kidney Diseases · 2001 · 224 citations

, , +12