Renal Circadian Clock Regulates the Dosing-Time Dependency of Cisplatin-Induced Nephrotoxicity in Mice

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Nicolas Preitner, Francesca Damiola, Luis Lopez‐Molina et al. · Cell · 2002 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

Nicholas Gekakis, David Staknis, Hubert B. Nguyen et al. · Science · 1998 · 2K citations

Life Sciences, Genetics, Molecular Biology +16

PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

Giulia Chinetti, Sophie Lestavel, Virginie Bocher et al. · Nature Medicine · 2001 · 1.2K citations

Life Sciences, Biochemistry, Pharmacology +17

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

H. Keller, C Dreyer, Jeffrey A. Medin et al. · Proceedings of the National Academy of Sciences · 1993 · 949 citations

Life Sciences, Biochemistry, Molecular Biology +17

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

Xiaowei Jin, Lauren P. Shearman, David R. Weaver et al. · Cell · 1999 · 892 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14