Peroxisome Proliferator-Activated Receptor γ Antagonists Decrease Na+ Transport via the Epithelial Na+ Channel

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

Marcus Mall, Barbara R. Grubb, Jack R. Harkema et al. · Nature Medicine · 2004 · 899 citations

Veterinary Medicine, Cell Biology, Pathobiology +12

Epithelial sodium channel regulated by aldosterone-induced protein sgk

Sei-Yu Chen, Aditi Bhargava, Luca Mastroberardino et al. · Proceedings of the National Academy of Sciences · 1999 · 739 citations

Life Sciences, Endocrinology, Physiology +17

Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption

You Fei Guan, Chuan‐Ming Hao, Dae Ryong et al. · Nature Medicine · 2005 · 602 citations

Medicine, Nephrology, Pharmacology +16

T0070907, a Selective Ligand for Peroxisome Proliferator-activated Receptor γ, Functions as an Antagonist of Biochemical and Cellular Activities

Gary Lee, Fabienne Elwood, John McNally et al. · Journal of Biological Chemistry · 2002 · 320 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Collecting duct-specific deletion of peroxisome proliferator-activated receptor γ blocks thiazolidinedione-induced fluid retention

Hui Zhang, Aihua Zhang, Donald E. Kohan et al. · Proceedings of the National Academy of Sciences · 2005 · 318 citations

Life Sciences, Pharmacology, Physiology +15