Concepedia

Rate-limiting Absorption

Rate-Limiting Absorption is a kinetic process in pharmacokinetics whereby the overall rate of drug absorption into systemic circulation is governed primarily by the slowest step in the sequence of absorption mechanisms, typically membrane permeation or dissolution, thereby determining the time course and extent of bioavailability.

97

Publications

5K

Citations

375

Authors

136

Institutions

Publications per year

2017–2026

9

Parents

Publications

97

Pharmacokinetics of Celecoxib after Oral Administration in Dogs and Humans: Effect of Food and Site of Absorption

Susan K. Paulson, Margaret B. Vaughn, Susan M. Jessen et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 286 citations

, , +17

Regulation of the Epithelial Sodium Channel by Serine Proteases in Human Airways

Scott H. Donaldson, Andrew J. Hirsh, Dong Chen Li et al. · Journal of Biological Chemistry · 2002 · 249 citations · Full text

, , +17

Albumin absorption and catabolism by isolated perfused proximal convoluted tubules of the rabbit.

C H Park, Thomas Maack · Journal of Clinical Investigation · 1984 · 210 citations · Full text

, , +12

5-Hydroxytryptophan: a clinically-effective serotonin precursor.

Timothy C. Birdsall · PubMed · 1998 · 203 citations

, , +14

Accelerated Fat Absorption in Intestinal Alkaline Phosphatase Knockout Mice

Sonoko Narisawa, Lei Huang, Arata Iwasaki et al. · Molecular and Cellular Biology · 2003 · 200 citations · Full text

, , +17

1–5 of 97

Authors

375

  1. DG
    David G. Levitt

    University of Minnesota, United States

    4 publications · 223 citations

    4

    h-index

  2. PR
    Peter Rejto

    University of Minnesota, United States

    3 publications · 49 citations

    3

    h-index

  3. AD
    Allen Devinatz

    Northwestern University, United States

    2 publications · 36 citations

    2

    h-index

  4. JK
    Julie Kneip

    Minneapolis VA Medical Center, United States

    2 publications · 101 citations

    2

    h-index

  5. JM
    John M. Beals

    Eli Lilly (United States), United States

    2 publications · 106 citations

    2

    h-index

1–5 of 375

Institutions

136

  1. United States Department of Veterans Affairs

    Washington, United States

    3 h-index

    7 publications

    367 citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    7 publications

    590 citations

  3. University of Minnesota

    Minneapolis, United States

    3 h-index

    4 publications

    75 citations

  4. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    9 publications

    300 citations

  5. Medical University of South Carolina

    Charleston, United States

    2 h-index

    2 publications

    329 citations

  6. University at Buffalo, State University of New York

    Buffalo, United States

    2 h-index

    5 publications

    233 citations

  7. AstraZeneca (Sweden)

    Södertälje, Sweden

    2 h-index

    4 publications

    101 citations

  8. University of Tennessee Health Science Center

    Memphis, United States

    2 h-index

    4 publications

    260 citations

1–8 of 136

Venues

  1. Journal of Clinical Investigation

    JCI · 4 publications · 394 citations

    4

    h-index

  2. 4

    h-index

  3. PLANT PHYSIOLOGY

    3 publications · 111 citations

    3

    h-index

  4. 3

    h-index

  5. Chemical and Pharmaceutical Bulletin

    3 publications · 35 citations

    3

    h-index

1–5