FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

Pharmacotherapy, Chemistry, Drug Resistance +21

Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease

Teresa Gómez‐Isla, Joseph L. Price, Daniel W. McKeel et al. · Journal of Neuroscience · 1996 · 1.8K citations · Full text

Expanded dynamic range of fluorescent indicators for Ca ²⁺ by circularly permuted yellow fluorescent proteins

Takeharu Nagai, Shuichi Yamada, Takashi Tominaga et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations

Huiping Tu, Omar L. Nelson, Arseny Bezprozvanny et al. · Cell · 2006 · 681 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +9

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

King‐Ho Cheung, Diana W. Shineman, Marioly Müller et al. · Neuron · 2008 · 448 citations · Full text

Signal Transduction, Alzheimer's Disease, Insp3 Receptor Channel +12