Concepedia

Functional responses and in vivo anti-tumour activity of h7C10: A humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors

Giuseppe Pandini, Thierry Wurch, Barbara Akla, Nathalie Corvaı̈a, Antonino Belfiore, Liliane Goetsch

European Journal of Cancer · 2007 · 73 citations · 37 references

DOI

Concepts

References

37

Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cells

Francesco Frasca, Giuseppe Pandini, Pierluigi Scalia et al. · Molecular and Cellular Biology · 1999 · 888 citations · Full text

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Insulin-like Growth Factor-I Receptor/Human Epidermal Growth Factor Receptor 2 Heterodimerization Contributes to Trastuzumab Resistance of Breast Cancer Cells

Rita Nahta, Linda X.H. Yuan, Bing Zhang et al. · Cancer Research · 2005 · 792 citations

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Carlos Garcı́a-Echeverrı́a, Mark Pearson, Andreas Marti et al. · Cancer Cell · 2004 · 535 citations · Full text

, , +9

Insulin/Insulin-like Growth Factor I Hybrid Receptors Have Different Biological Characteristics Depending on the Insulin Receptor Isoform Involved

Giuseppe Pandini, Francesco Frasca, Rossana Mineo et al. · Journal of Biological Chemistry · 2002 · 490 citations · Full text

Monoclonal antibodies to receptors for insulin and somatomedin-C.

Frederick C. Kull, Steven Jacobs, Y F Su et al. · Journal of Biological Chemistry · 1983 · 422 citations · Full text

, , +15