Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.3K citations · Full text

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

Daniel Fishman, Gary Faulds, Rachel Jeffery et al. · Journal of Clinical Investigation · 1998 · 2.2K citations · Full text

Il-6 Genotype, Immunology, Genetic Epidemiology +24

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis

Jeffrey R. O'Connell, Daniel E. Weeks · The American Journal of Human Genetics · 1998 · 2.1K citations · Full text

Genetic Analysis, Haplotype Determination, Linkage Disequilibrium +12

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

Mark H. Kaplan, Ulrike Schindler, Stephen T. Smiley et al. · Immunity · 1996 · 1.6K citations · Full text

Inflammation, Cytokine, Th2 Cells +10

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Kazuya Shimoda, Jan van Deursent, Mark Y. Sangster et al. · Nature · 1996 · 1.3K citations

Inflammation, Immunogenetics, Il-4-induced Th2 Response +10