Concepedia

Design and synthesis of novel platelet fibrinogen receptor antagonists with 2H-1,4-benzoxazine-3(4H)-one scaffold. A systematic study

Marko Anderluh, Jožko Cesar, Petra Peharec Štefanić, D. Kikelj, Damjan Janeš, Jernej Murn, Kristina Nadrah, Mojca Tominc, Elisabeth Addicks, Athanassios Giannis,

European Journal of Medicinal Chemistry · 2004 · 41 citations · 25 references

DOI

Concepts

References

25

The aggregation of blood platelets

G. V. R. Born, Michael Cross · The Journal of Physiology · 1963 · 2.1K citations

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Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

Jian-Ping Xiong, Thilo Stehle, Rongguang Zhang et al. · Science · 2002 · 1.6K citations

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Crystal Structure of the Extracellular Segment of Integrin αVβ3

Jian-Ping Xiong, Thilo Stehle, Beate Diefenbach et al. · Science · 2001 · 1.3K citations · Full text

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Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

Xiaoping Du, Edward F. Plow, Andrew L. Frelinger et al. · Cell · 1991 · 490 citations

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Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.

Andrew L. Frelinger, Xiaoping Du, Edward F. Plow et al. · Journal of Biological Chemistry · 1991 · 359 citations · Full text

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