Concepedia

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

Marta Martínez‐Vicente, Zsolt Tallóczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,

Nature Neuroscience · 2010 · 858 citations · 38 references

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38

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

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Autophagy regulates lipid metabolism

Rajat Singh, Susmita Kaushik, Yongjun Wang et al. · Nature · 2009 · 3.9K citations · Full text

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Gilad Twig, Álvaro A. Elorza, Anthony Molina et al. · The EMBO Journal · 2008 · 3.1K citations · Full text

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

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