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Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

Irina N. Shalova, Jyue Yuan Lim, Manesh Chittezhath, Annelies S. Zinkernagel, Federico C. Beasley, Enrique Hernández-Jiménez, Víctor Toledano, Carolina Cubillos‐Zapata, Annamaria Rapisarda, Jinmiao Chen,

Immunity · 2015 · 419 citations · 33 references

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33

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

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Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer et al. · Molecular and Cellular Biology · 1996 · 4K citations · Full text

, , +15

Genomic responses in mouse models poorly mimic human inflammatory diseases

Junhee Seok, H. Shaw Warren, Alex G. Cuenca et al. · Proceedings of the National Academy of Sciences · 2013 · 3K citations · Full text

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Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo et al. · Nature · 2014 · 2.9K citations

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Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

Theodore J. Iwashyna, E. Wesley Ely, Dylan M. Smith et al. · JAMA · 2010 · 2.6K citations

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