Nrf2 is a novel regulator of bone acquisition

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Patricia Ducy, Rui Zhang, Valérie Geoffroy et al. · Cell · 1997 · 4.3K citations · Full text

Medicine, Genetics, Molecular Biology +11

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

Toshihisa Komori, Hideshi Yagi, Shogo Nomura et al. · Cell · 1997 · 4.2K citations · Full text

Medicine, Developmental Biology, Orthopedic Surgery +16

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Hiroshi Takayanagi, Sunhwa Kim, Takako Koga et al. · Developmental Cell · 2002 · 2.7K citations · Full text

Medicine, Cell Biology, Molecular Biology +16

Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology · 2004 · 2.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Albena T. Dinkova‐Kostova, W. David Holtzclaw, Robert N. Cole et al. · Proceedings of the National Academy of Sciences · 2002 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16