Concepedia

Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm

A. Phillip Owens, Todd L. Edwards, Silvio Antoniak, Julia E. Geddings, Eiman Jahangir, Wei‐Qi Wei, Joshua C. Denny, Yacine Boulaftali, Wolfgang Bergmeier, Alan Daugherty,

Arteriosclerosis Thrombosis and Vascular Biology · 2015 · 85 citations · 48 references

DOIFull text

Open access

Abstract

These results suggest that platelets contribute to abdominal aortic aneurysm progression and rupture.

References

48

Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E–deficient mice

Alan Daugherty, Michael W. Manning, Lisa A. Cassis · Journal of Clinical Investigation · 2000 · 1.4K citations · Full text

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

G. Matthew Longo, Wanfen Xiong, Timothy C. Greiner et al. · Journal of Clinical Investigation · 2002 · 982 citations · Full text

Vorapaxar in the Secondary Prevention of Atherothrombotic Events

David A. Morrow, Eugene Braunwald, Marc P. Bonaca et al. · New England Journal of Medicine · 2012 · 927 citations · Full text

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

Robert Pyo, Jason K. Lee, J. Michael Shipley et al. · Journal of Clinical Investigation · 2000 · 823 citations · Full text

Abdominal Aortic Aneurysm Expansion

Simon G. Thompson, F. Gerald R. Fowkes, Roger M. Greenhalgh et al. · Circulation · 2004 · 681 citations