Joshua C. Denny

A gene-based association method for mapping traits using reference transcriptome data

Eric R. Gamazon, Kaanan P. Shah, Sahar V. Mozaffari et al. · Nature Genetics · 2015 · 2.1K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Wei Zhou, Jonas B. Nielsen, Lars G. Fritsche et al. · Nature Genetics · 2018 · 1.6K citations

Public Health, Biostatistics, Genetics +14

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations

Joshua C. Denny, Marylyn D. Ritchie, Melissa Basford et al. · Bioinformatics · 2010 · 1.3K citations · Full text

Medicine, Biomedical Informatics, Molecular Genetics +16

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

Joshua C. Denny, Lisa Bastarache, Marylyn D. Ritchie et al. · Nature Biotechnology · 2013 · 1.1K citations · Full text

Medicine, Bioinformatics, Biomedical Informatics +16