Journal of the Science of Food and Agriculture · 1988 · 59 citations · 9 references
PharmacyEnvironmental SciencesToxicologyAnalytical ToxicologyEnvironmental ToxicologyFood AnalysisCarcinogenicity AssessmentFood ToxicantsAromatic HydrocarbonsBenzo[a]pyrene ExposureColumn ChromatographyPolycyclic Aromatic Hydrocarbon AnalysisPolycyclic Aromatic Hydrocarbon ToxicologyPolycyclic Aromatic HydrocarbonsPrimary Liver CancerPrimary Liver Tumors
Abstract Chemical analyses of kundi show that, apart from a high level of carcinogenic benzo ( a )pyrene (10·5–66·9 ng g −1 ), eight other polycyclic aromatic hydrocarbons (PAH) are present at various concentrations. The high levels of PAH in kundi are due to the high glow and smoking temperatures averaging 926°C and 191·5°C, respectively. Column chromatography was used for PAH extraction with propylene carbonate as the eluting chemical; thin layer chromatography (TLC) on acetylated cellulose layer plates was used for separation, and the determination was performed using spectrophotofluorimetry. The public health implications of PAH as one of the possible carcinogenic factors in the high incidence of primary liver and stomach cancer reported in Nigeria are highlighted.
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Survey of Compounds Which Have Been Tested for Carcinogenic Activity
JAMA · 1942 · 347 citations
Polycyclic Hydrocarbons in Icelandic Smoked Food
Esmé J Bailey, Niels Dungal · British Journal of Cancer · 1958 · 48 citations · Full text