Concepedia

An open-label study to evaluate dose and cycle dependence of the pharmacokinetics of pegylated liposomal doxorubicin

Alberto Gabizón, Rut Isacson, Ora Rosengarten, Dina Tzemach, Hilary Shmeeda, Rama Sapir

Cancer Chemotherapy and Pharmacology · 2007 · 111 citations · 27 references

DOI

Concepts

References

27

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

E O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology · 2004 · 1.7K citations · Full text

, , +17

Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes.

Alberto Gabizón, Raphael Catane, Beatrice Uziely et al. · PubMed · 1994 · 1.4K citations

, , +13

Recurrent Epithelial Ovarian Carcinoma: A Randomized Phase III Study of Pegylated Liposomal Doxorubicin Versus Topotecan

Alan N. Gordon, John Fleagle, David Guthrie et al. · Journal of Clinical Oncology · 2001 · 1.2K citations

, , +16

Sterically stabilized liposomes

Martin C. Woodle · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · 1992 · 950 citations

Pegylated liposomal doxorubicin (doxil): Reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2

Tamar Safra, Franco M. Muggia, Susan Jeffers et al. · Annals of Oncology · 2000 · 613 citations

, , +16