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Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

C F Starmer, Augustus O. Grant, Harold C. Strauss

Biophysical Journal · 1984 · 341 citations · 30 references

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References

30

A quantitative description of membrane current and its application to conduction and excitation in nerve

A. L. Hodgkin, A. F. Huxley · The Journal of Physiology · 1952 · 23.2K citations · Full text

, , +12

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

, , +16

The dual effect of membrane potential on sodium conductance in the giant axon of <i>Loligo</i>

A. L. Hodgkin, A. F. Huxley · The Journal of Physiology · 1952 · 1.6K citations · Full text

, , +17

Effects of calcium ions and local anaesthetics on electrical properties of Purkinje fibres

Silvio Weidmann · The Journal of Physiology · 1955 · 703 citations · Full text

, , +13

The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine

Gary R. Strichartz · The Journal of General Physiology · 1973 · 665 citations · Full text

, , +17