Concepedia

Local Anesthetics

Local Anesthetics is a class of pharmacological agents that produce a reversible loss of sensation in a localized area by selectively blocking voltage-gated sodium channels in peripheral nerves, thereby interrupting nerve impulse conduction without causing loss of consciousness.

3.2K

Publications

151.1K

Citations

8.3K

Authors

2.1K

Institutions

Publications per year

2017–2026

159

Variants

Local Anesthetic Agents

Parents

Children

Publications

3.2K

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

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Molecular Determinants of State-Dependent Block of Na <sup>+</sup> Channels by Local Anesthetics

David S. Ragsdale, Jancy C. McPhee, Todd Scheuer et al. · Science · 1994 · 861 citations

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Local anaesthetics transiently block currents through single acetylcholine‐receptor channels.

Erwin Neher, Joe Henry Steinbach · The Journal of Physiology · 1978 · 849 citations · Full text

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Neural Blockade in Clinical Anesthesia and Management of Pain

Michael J. Cousins, Phillip O. Bridenbaugh, Philadelphia J. B. Lippincott · Anesthesiology · 1981 · 828 citations · Full text

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Acute Toxicity of Ropivacaine Compared with That of Bupivacaine

D.B. SCOTT, Alistair Lee, D. Fagan et al. · Anesthesia & Analgesia · 1989 · 772 citations

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1–5 of 3.2K

Authors

8.3K

  1. GR
    Gary R. Strichartz

    Brigham and Women's Hospital, United States

    40 publications · 2.9K citations

    30

    h-index

  2. DS
    Daniel S. Kohane

    Harvard University, United States

    29 publications · 2K citations

    27

    h-index

  3. BG
    Benjamín G. Covino

    Brigham and Women's Hospital, United States

    32 publications · 2.5K citations

    25

    h-index

  4. GK
    Ging Kuo Wang

    Brigham and Women's Hospital, United States

    25 publications · 1.3K citations

    18

    h-index

  5. ME
    Marcel E. Durieux

    University of Virginia, United States

    19 publications · 841 citations

    15

    h-index

1–5 of 8.3K

Institutions

2.1K

  1. Brigham and Women's Hospital

    Boston, United States

    50 h-index

    243 publications

    17.3K citations

  2. Harvard University

    Cambridge, United States

    47 h-index

    283 publications

    17K citations

  3. Marymount University

    Arlington, United States

    31 h-index

    79 publications

    4.4K citations

  4. Boston Children's Hospital

    Boston, United States

    28 h-index

    141 publications

    8.5K citations

  5. University of Washington

    Seattle, United States

    25 h-index

    96 publications

    11.6K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    21 h-index

    71 publications

    5.6K citations

  7. University of California, San Francisco

    San Francisco, United States

    20 h-index

    56 publications

    7.6K citations

  8. University of Toronto

    Toronto, Canada

    20 h-index

    64 publications

    4.5K citations

1–8 of 2.1K

Venues

  1. Anesthesia & Analgesia

    285 publications · 17.8K citations

    72

    h-index

  2. Anesthesiology

    238 publications · 14.7K citations

    69

    h-index

  3. PubMed

    Repository · 254 publications · 7.5K citations

    44

    h-index

  4. British Journal of Anaesthesia

    131 publications · 7K citations

    44

    h-index

  5. Regional Anesthesia & Pain Medicine

    RAPM · 100 publications · 4.3K citations

    37

    h-index

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