Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Celina G. Kleer, Qi Cao, Sooryanarayana Varambally et al. · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

Medicine, Molecular Biology, Oncology +17

EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer

Adrian P. Bracken · The EMBO Journal · 2003 · 1.2K citations · Full text

Medicine, Cancer Biology, Molecular Biology +12

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

Jing Tan, Xiaojing Yang, Li Zhuang et al. · Genes & Development · 2007 · 898 citations · Full text

Life Sciences, Genetics, Oncology +17

EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast

Ingeborg Bachmann, Ole J. Halvorsen, Karin Collett et al. · Journal of Clinical Oncology · 2005 · 844 citations

Medicine, Genetics, Oncology +17