Concepedia

Capsular Switching in Group B Streptococcus CC17 Hypervirulent Clone: A Future Challenge for Polysaccharide Vaccine Development

Samuel Bellais, Anne Six, Agnès Fouet, M. Longo, Nicolas Dmytruk, Philippe Glaser, Patrick Trieu‐Cuot, Claire Poyart

The Journal of Infectious Diseases · 2012 · 142 citations · 40 references

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Abstract

This work shows that GBS CC17 hypervirulent strains have switched one of their main vaccine targets. Thus, continued surveillance of GBS population remains of the utmost importance during clinical trials of conjugate GBS vaccines.

References

40

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Nicola Jones, John F. Bohnsack, Shinji Takahashi et al. · Journal of Clinical Microbiology · 2003 · 610 citations · Full text

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Philippe Glaser, Christophe Rusniok, Carmen Buchrieser et al. · Molecular Microbiology · 2002 · 472 citations · Full text