Concepedia

A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

Dong‐Hyun Kim, Zhen Xiao, Sang‐Hoon Kwon, Xiaoxiao Sun, Daniel Ryerson, David Tkac, Ping Ma, Shwu‐Yuan Wu, Cheng‐Ming Chiang, Edward Zhou,

The EMBO Journal · 2014 · 122 citations · 31 references

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Concepts

References

31

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

Chunaram Choudhary, Chanchal Kumar, Florian Gnad et al. · Science · 2009 · 4K citations · Full text

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Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

Joseph T. Rodgers, Carles Lerín, Wilhelm Haas et al. · Nature · 2005 · 3.1K citations

, , +14

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Shimin Zhao, Wei Xu, Wenqing Jiang et al. · Science · 2010 · 1.9K citations

, , +15

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

Jun Yoshino, Kathryn F. Mills, Myeong Jin Yoon et al. · Cell Metabolism · 2011 · 1.3K citations · Full text

, , +15

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

Gabriel Pascual, Amy L. Fong, Sumito Ogawa et al. · Nature · 2005 · 1.2K citations · Full text

, , +14