Model Reactions for the Stereo‐Controlled Synthesis of Aminopolyols; Reduction of Isoxazolines with Free or Protected Hydroxy Groups in Position 4 or in Side Chains

Abstract

The effects of substituents on asymmetric induction in hydride additions have been investigated on isoxazoline derivatives; the results, which are of importance for the synthesis of hydroxylated amino acids, sphingolipid bases or amino sugars, can be rationalized with the models (1) and (2).

References

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