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Primary sclerosing cholangitis: findings on cholangiography and pancreatography.

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1983

Year

TLDR

Cholangiograms of 86 PSC patients were compared with those of 82 primary bile duct carcinoma patients and 16 primary biliary cirrhosis patients. PSC cholangiograms show multifocal, short, annular strictures producing a beaded appearance, occasional band‑like strictures and diverticula, findings specific to PSC, with 66 % of patients having inflammatory bowel disease that is not distinguishable cholangiographically, and only 3 of 40 patients with pancreatograms exhibiting pancreatic duct abnormalities.

Abstract

Cholangiograms of 86 patients with primary sclerosing cholangitis (PSC) were compared with those of 82 patients with primary bile duct carcinoma and 16 with primary biliary cirrhosis. Multifocal strictures involving both intra- and extra-hepatic bile ducts were most common in PSC; they were diffusely distributed, short, and annular, alternating with normal or slightly dilated segments to produce a "beaded" appearance. Very short, band-like strictures occurred in 18 patients; 9 also had diverticulum-like out-pouchings. Fourteen patients had "diverticula" without band strictures. Both findings appear to be specific for PSC. Inflammatory bowel disease was seen in 57 patients (66%), who could not be distinguished cholangiographically from other PSC patients. Of 40 patients with adequate retrograde pancreatograms, 3 had abnormalities of the pancreatic ducts.