Concepedia

Discovery of 4-Pyridone Derivatives as Specific Inhibitors of Enoyl-Acyl Carrier Protein Reductase (FabI) with Antibacterial Activity against Staphylococcus aureus

Sho Takahata, Maiko Iida, Takuji Yoshida, Ko Kumura, Hideo Kitagawa, Shigeru Hoshiko

The Journal of Antibiotics · 2007 · 28 citations · 16 references

DOI

Concepts

References

16

Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

Mary Jane Ferraro · 2000 · 16.9K citations

, , +10

Genes <i>acrA</i> and <i>acrB</i> encode a stress‐induced efflux system of <i>Escherichia coli</i>

Dzwokai Ma, David N. Cook, Marie Alberti et al. · Molecular Microbiology · 1995 · 609 citations

, , +17

Mechanism of Triclosan Inhibition of Bacterial Fatty Acid Synthesis

Richard J. Heath, John R. Rubin, Debra R. Holland et al. · Journal of Biological Chemistry · 1999 · 547 citations · Full text

, , +15

Enoyl-Acyl Carrier Protein Reductase (fabI) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation in Escherichia coli

Richard J. Heath, Charles O. Rock · Journal of Biological Chemistry · 1995 · 369 citations · Full text

, , +16

Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis

James C. Sacchettini, Andréa Dessen, Catherine Vilchèze et al. · Biochemistry · 1995 · 368 citations

, , +11