James C. Sacchettini

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

John D. McKinney, Kerstin Höner zu Bentrup, Ernesto J. Muñoz‐Elías et al. · Nature · 2000 · 1.3K citations · Full text

Medical Microbiology, Pulmonary Tuberculosis, Biochemistry +7

Modification of the NADH of the Isoniazid Target (InhA) from <i>Mycobacterium tuberculosis</i>

Denise A. Rozwarski, Gregory A. Grant, D. H. R. BARTON et al. · Science · 1998 · 674 citations

Isoniazid Target, Cellular Enzymology, Biochemistry +13

Crystal Structure and Function of the Isoniazid Target of <i>Mycobacterium tuberculosis</i>

Andréa Dessen, Annaı̈k Quémard, John S. Blanchard et al. · Science · 1995 · 428 citations

Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis

James C. Sacchettini, Andréa Dessen, Catherine Vilchèze et al. · Biochemistry · 1995 · 368 citations

Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid

Catherine Vilchèze, Feng Wang, Masayoshi Arai et al. · Nature Medicine · 2006 · 321 citations

Pulmonary Tuberculosis, Pathogenesis, Tuberculosis Prevention +8