Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis

Abstract

Injured podocytes in active LN express TLR9. This expression could be associated with proteinuria and increased anti-dsDNA antibody. This is the first report indicating that TLR9 is involved in the aetiology of LN and that it may play some role in podocyte injury.