Alberta Stroke Program Early CT Score (ASPECTS) in Patients With Wake-Up Stroke

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine · 2008 · 6.6K citations · Full text

Medicine, Neurology, Neurocritical Care +11

Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy

Philip A. Barber, Andrew M. Demchuk, Jinjin Zhang et al. · The Lancet · 2000 · 2.6K citations

Medicine, Clinical Sciences, Neurology +16

Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

Stephen M. Davis, Geoffrey A. Donnan, Mark Parsons et al. · The Lancet Neurology · 2008 · 1K citations

Medicine, Neurology, Radiology +14

Why are stroke patients excluded from TPA therapy?

P A Barber, Joyce L. Zhang, Andrew M. Demchuk et al. · Neurology · 2001 · 708 citations

Medicine, Emergency Medicine, Neurology +14

Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion–diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study

Werner Hacke, Anthony J. Furlan, Yasir Al‐Rawi et al. · The Lancet Neurology · 2008 · 569 citations · Full text

Medicine, Neurology, Radiology +16