Molecular Imaging of Activated Matrix Metalloproteinases in Vascular Remodeling

Jiasheng Zhang, Lei Nie, Mahmoud Razavian, Masood Ahmed, Lawrence W. Dobrucki, Abolfazl Asadi, David S. Edwards, Michael Azure, Albert J. Sinusas, Mehran M. Sadeghi

Circulation · 2008 · 103 citations · 31 references

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Abstract

Injury-induced MMP activation in the vessel wall can be detected by RP782 microSPECT/CT imaging in vivo. RP782 uptake tracks the hyperplastic process in vascular remodeling and provides an opportunity to track the remodeling process in vivo.

References

31