Concepedia

Prediction of Renal Transporter Mediated Drug-Drug Interactions for Pemetrexed Using Physiologically Based Pharmacokinetic Modeling

Maria M. Posada, James A. Bacon, Karen Schneck, Rommel G. Tirona, Richard B. Kim, J. William Higgins, Y. Anne Pak, Stephen D. Hall, Kathleen M. Hillgren

Drug Metabolism and Disposition · 2014 · 57 citations · 47 references

DOI

Concepts

References

47

Prediction of Creatinine Clearance from Serum Creatinine

Donald W. Cockcroft, Henry Gault · ˜The œNephron journals/Nephron journals · 2008 · 15.4K citations

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In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

Shiyin Yee · Pharmaceutical Research · 1997 · 1K citations

, , +13

Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Trudy Rodgers, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2006 · 940 citations

, , +11

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 774 citations

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OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

Mirjana Cvetković, Brenda F. Leake, Martin F. Fromm et al. · Drug Metabolism and Disposition · 1999 · 595 citations

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