Concepedia

Polo-Box Domain Inhibitor Poloxin Activates the Spindle Assembly Checkpoint and Inhibits Tumor Growth in Vivo

Juping Yuan, Mourad Sanhaji, Andrea Krämer, Wolfgang Reindl, Matthias Hofmann, Nina‐Naomi Kreis, Brigitte Zimmer, Thorsten Berg, Klaus Strebhardt

American Journal Of Pathology · 2011 · 94 citations · 39 references

DOIFull text

Open access

Concepts

References

39

BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Martin Steegmaier, Matthias Hoffmann, Anke Baum et al. · Current Biology · 2007 · 849 citations · Full text

, , +14

The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

Andrew E. H. Elia, Peter Rellos, L.F. Haire et al. · Cell · 2003 · 769 citations · Full text

, , +11

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes.

Heidi A. Lane, Erich A. Nigg · The Journal of Cell Biology · 1996 · 690 citations · Full text

, , +15

The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Péter Lénárt, Mark Petronczki, Martin Steegmaier et al. · Current Biology · 2007 · 677 citations · Full text

, , +17

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

Roy M. Golsteyn, Kirsten Mundt, Andrew M. Fry et al. · The Journal of Cell Biology · 1995 · 479 citations · Full text

, , +17