Allosteric Modulation of Binding Properties between Units of Chemokine Receptor Homo- and Hetero-Oligomers

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

Agonist-specific Binding Properties, Experimental Pharmacology, Ternary Complex Hrx +17

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin

David Farrens, Christian Altenbach, Ke Yang et al. · Science · 1996 · 1.2K citations

Rhodopsin dimers in native disc membranes

Dimitrios Fotiadis, Yan Liang, Sławomir Filipek et al. · Nature · 2003 · 739 citations

Proteinlipid Interaction, Membrane Transport, Membrane System +3

Insulin interactions with its receptors: Experimental evidence for negative cooperativity

Pierre De Meyts, Jesse Roth, David M. Neville et al. · Biochemical and Biophysical Research Communications · 1973 · 722 citations

Signal Transduction, Biochemistry, Functional Selectivity +9

Quantitative Assessment of β1- and β2-Adrenergic Receptor Homo- and Heterodimerization by Bioluminescence Resonance Energy Transfer

Jean‐François Mercier, Ali Salahpour, Stéphane Angers et al. · Journal of Biological Chemistry · 2002 · 469 citations · Full text

β2-Adrenergic Receptor Homo-, Cellular Physiology, Molecular Pharmacology +20