Synthesis and structure-activity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A. Cherny, Craig Atwood, Michel Xilinas et al. · Neuron · 2001 · 1.5K citations · Full text

Life Sciences, Neuroscience, Pharmacology +13

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease

Craig Ritchie, Ashley I. Bush, Andrew Mackinnon et al. · Archives of Neurology · 2003 · 982 citations

Life Sciences, Pharmacology, Pharmacotherapy +17

Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

Linghang Zhuang, John Wai, Mark W. Embrey et al. · Journal of Medicinal Chemistry · 2003 · 270 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Fluorogenic Hg²⁺-Selective Chemodosimeter Derived from 8-Hydroxyquinoline

Ki Cheol Song, Jun Soo Kim, Sang Mi Park et al. · Organic Letters · 2006 · 262 citations

Natural Sciences, Chemistry, Drug Discovery +8

Anticancer Activity of the Antibiotic Clioquinol

Wei‐Qun Ding, Bolin Liu, Joshua L. Vaught et al. · Cancer Research · 2005 · 250 citations

Medicine, Oncology, Pharmacology +13