Concepedia

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

John H. Kehne, B M Baron, A A Carr, S. Chaney, Jack Elands, Daniel J. Feldman, Robert Frank, P L van Giersbergen, Timothy C. McCloskey, Martin Johnson,

Journal of Pharmacology and Experimental Therapeutics · 1996 · 359 citations · 0 references

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Concepts

MedicineMedicinal ChemistryPharmacologyMolecular PharmacologyNeuropharmacologyPsychopharmacologyAntipsychotic PharmacologyAntipsychotic PharmacotherapyAntipsychotic TherapySerotonergic PharmacologySerotonergic Signaling5-Hydroxytryptamine Receptor PharmacologyAntipsychotic ActionAntipsychotic SafetyAtypical Antipsychotic TreatmentReceptor Binding ProfilesReceptorsSerotonin AntagonistsSerotonin Receptor Pharmacology