Timothy C. McCloskey

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

John H. Kehne, B M Baron, A A Carr et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 358 citations · Full text

NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations

John H. Kehne, Timothy C. McCloskey, Bruce M. Baron et al. · European Journal of Pharmacology · 1991 · 127 citations

Potential Anxiolytic Effects, Medicine, Mechanism Of Action +6

5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100,907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats

Robert Padich, Timothy C. McCloskey, John H. Kehne · Psychopharmacology · 1996 · 120 citations

Optogenetics, 5-Ht Modulation, Visual Sensorimotor Gating +14

Buspirone effects in an animal conflict procedure: Comparison with diazepam and phenobarbital

Timothy C. McCloskey, Brian K. Paul, Randall L. Commissaris · Pharmacology Biochemistry and Behavior · 1987 · 76 citations

Animal Conflict Procedure, Neurophysiology, Behavioral Neuroscience +11

5-HT modulation of auditory and visual sensorimotor gating: I. Effects of 5-HT releasers on sound and light prepulse inhibition in Wistar rats

John H. Kehne, Robert Padich, Timothy C. McCloskey et al. · Psychopharmacology · 1996 · 72 citations

Visual Sensorimotor Gating, Brain Mechanism, Inhibitory Process +16