P L van Giersbergen

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

John H. Kehne, B M Baron, A A Carr et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 359 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Effects of the Endothelin Receptor Antagonist Bosentan on Hemodynamics, Symptoms and Functional Capacity in Japanese Patients With Severe Pulmonary Hypertension

Shigetake Sasayama, Takeyoshi Kunieda, Hitonobu Tomoike et al. · Circulation Journal · 2005 · 46 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist.

Elizabeth M. Kudlacz, Scott A. Shatzer, Robert W. Knippenberg et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Antagonism by naltrexone of the hypotension and bradycardia induced by alpha-methyldopa in conscious normotensive rats.

P L van Giersbergen, Wybren de Jong · Journal of Pharmacology and Experimental Therapeutics · 1988 · 27 citations

Medicine, Neurobiology, Pharmacology +16

Effects of dynorphin A(1 – 13) and of fragments of β-endorphin on blood pressure and heart rate of anesthetized rats

P L van Giersbergen, H. De Lang, Wybren de Jong · Canadian Journal of Physiology and Pharmacology · 1991 · 24 citations

Medicine, Neurobiology, Pharmacology +17