Large scale H.E.L.P. synthesis of oligodeoxynucleotides by the hydroxybenzotriazole phosphotriester approach.

Crystal structure analysis of a complete turn of B-DNA

Richard M. Wing, Horace R. Drew, Tsunehiro Takano et al. · Nature · 1980 · 861 citations

Crystal Structure, Complete Turn, Molecular Biology +3

The chemical synthesis of oligo- and poly-nucleotides by the phosphotriester approach

Colin B. Reese · Tetrahedron · 1978 · 313 citations

Biosynthesis, Engineering, Biochemistry +5

Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

Makoto Matsukura, Gerald Zon, Kazuo Shinozuka et al. · Proceedings of the National Academy of Sciences · 1989 · 263 citations · Full text

Viral Replication, Immunology, Molecular Biology +20

Molecular structure of the octamer d(G-G-C-C-G-G-C-C): modified A-DNA.

A H Wang, Satoshi Fujii, Jacques H. van Boom et al. · Proceedings of the National Academy of Sciences · 1982 · 195 citations · Full text

Dna Nanotechnology, Nucleic Acid Chemistry, Dna +15

Reaction between 1-arenesulphonyl-3-nitro-1,2,4-triazoles and nucleoside base residues. Elucidation of the nature of side-reactions during oligonucleotide synthesis.

Colin B. Reese, Aiko Ubasawa · Tetrahedron Letters · 1980 · 129 citations

Nucleic Acid Chemistry, Biochemistry, Natural Sciences +7