A Novel, Potent, and Selective Inhibitor of Cardiac Late Sodium Current Suppresses Experimental Arrhythmias

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

Qing Wang, Jiaxiang Shen, Igor Splawski et al. · Cell · 1995 · 1.7K citations · Full text

Medicine, Genetics, Molecular Genetics +14

Molecular mechanism for an inherited cardiac arrhythmia

Paul B. Bennett, Kazuto Yazawa, Naomasa Makita et al. · Nature · 1995 · 967 citations

Medicine, Cardiology, Molecular Genetics +13

Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.

Craig T. January, Janet Riddle · Circulation Research · 1989 · 679 citations · Full text

Medicine, Pharmacology, Physiology +17

Electrophysiological Effects of Ranolazine, a Novel Antianginal Agent With Antiarrhythmic Properties

Charles Antzelevitch, Luiz Belardinelli, Andrew C. Zygmunt et al. · Circulation · 2004 · 678 citations · Full text

Medicine, Cardiology, Pharmacology +17

Novel, Ultraslow Inactivating Sodium Current in Human Ventricular Cardiomyocytes

Victor A. Maltsev, Hani N. Sabbah, Robert Higgins et al. · Circulation · 1998 · 308 citations · Full text

Natural Sciences, Cardiology, Physiology +17