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Correlated Evolutionary Pressure at Interacting Transcription Factors and DNA Response Elements Can Guide the Rational Engineering of DNA Binding Specificity

Evolutionary PressureTranscription FactorsDna Binding SpecificityNatural SciencesGeneticsGenomic MechanismGene RegulationDna ReplicationMolecular BiologyRational EngineeringMolecular GeneticsGene StructureGene Regulatory NetworkGene ExpressionMedicineFunctional GenomicsGenome EditingTranscription Regulation