Correlated Evolutionary Pressure at Interacting Transcription Factors and DNA Response Elements Can Guide the Rational Engineering of DNA Binding Specificity

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

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Satisfying Hydrogen Bonding Potential in Proteins

Ian K. McDonald, Janet M. Thornton · Journal of Molecular Biology · 1994 · 2.1K citations

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An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families

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Life Sciences, Biochemistry, Bioinformatics +12

Sequence-specific recognition of double helical nucleic acids by proteins.

Nadrian C. Seeman, John M. Rosenberg, Alexander Rich · Proceedings of the National Academy of Sciences · 1976 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17