The effect of nanonization on poorly water soluble glibenclamide using a liquid anti-solvent precipitation technique: aqueous solubility, in vitro and in vivo study

Rohan D. Deshpande, D. V. Gowda, Naga Sravan Kumar Varma Vegesna, Rudra Vaghela, P. K. Kulkarni

RSC Advances · 2015 · 21 citations · 29 references

Concepts

Abstract

In the present study, efforts were made to optimize the process parameters of LAS technique for developing GLB NPs, in order to enhance the aqueous solubility as well as oral bioavailability.

References

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