Concepedia

KITENIN recruits Dishevelled/PKCδ to form a functional complex and controls the migration and invasiveness of colorectal cancer cells

Dhong Hyo Kho, J A Bae, J H Lee, Hyun Jin Cho, Seung Hyun Cho, J H Lee, Y-W Seo, Kyu Youn Ahn, Ik‐Joo Chung, K K Kim

Gut · 2008 · 82 citations · 18 references

DOI

Abstract

The functional KITENIN complex acts as an executor with regard to cell motility and thereby controls CRC cell invasion, which may contribute to promoting metastasis.

References

18

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

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Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

Ashani T. Weeraratna, Yuan Jiang, Galen Hostetter et al. · Cancer Cell · 2002 · 957 citations · Full text

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Wnt/Frizzled Activation of Rho Regulates Vertebrate Gastrulation and Requires a Novel Formin Homology Protein Daam1

Raymond Habas, Yoichi Kato, Xi He · Cell · 2001 · 820 citations · Full text

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Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer

Gillian Smith, Francis A. Carey, Julie Beattie et al. · Proceedings of the National Academy of Sciences · 2002 · 516 citations · Full text

The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos

Maiyon Park, Randall T. Moon · Nature Cell Biology · 2001 · 379 citations

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