Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

Florian Heil, Hiroaki Hemmi, Hubertus Hochrein et al. · Science · 2004 · 3.9K citations

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.8K citations

Essential Function, Viral Replication, Molecular Virology +10

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations

Rig-i Helicases, Virus Structure, Viral Replication +11

5'-Triphosphate RNA Is the Ligand for RIG-I

Veit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth et al. · Science · 2006 · 2.4K citations

Viral Replication, Systems Biology, Engineering +12

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Etienne Meylan, Joseph Curran, Kay Hofmann et al. · Nature · 2005 · 2.4K citations · Full text

Adaptor Protein, Rig-i Antiviral Pathway, Hepatitis C Virus +8