Timolol Metabolism in Human Liver Microsomes Is Mediated Principally by CYP2D6

References

Page 1

	Year	Citations
CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants L M Hesse, Karthik Venkatakrishnan, Michael H. Court, Drug Metabolism and Disposition	2000	397
Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity Stephanie Faucette, Roy L. Hawke, Edward L. LeCluyse, Drug Metabolism and Disposition	2000	355
Amodiaquine Clearance and Its Metabolism to N-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate Xueqing Li, Anders Björkman, Tommy B. Andersson, Journal of Pharmacology and Experimental Therapeutics	2002	284
Adverse Reactions from Timolol Administration E. Michael Van Buskirk Ophthalmology Drug HypersensitivityMedicinePharmacologyToxicologyPharmacotherapy	1980	282
Stereoselective Metabolism of Omeprazole by Human Cytochrome P450 Enzymes Angela Äbelö, Tommy B. Andersson, Madeleine Antonsson, Drug Metabolism and Disposition	2000	272
Adverse Respiratory and Cardiovascular Events Attributed to Timolol Ophthalmic Solution, 1978–1985 Wendy L. Nelson, Frederick T. Fraunfelder, Judith M. Sills, American Journal of Ophthalmology Adverse RespiratoryOcular DiseaseTimolol Ophthalmic SolutionAllergyOphthalmology	1986	258
Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops J.‐M. Korte, Timo Kaila, Matti K. Saari Graefe s Archive for Clinical and Experimental Ophthalmology Heart FailureOphthalmologyExperimental OphthalmologyGlaucomaMedicine	2002	156
SELECTIVE INHIBITION OF CYP2B6-CATALYZED BUPROPION HYDROXYLATION IN HUMAN LIVER MICROSOMES IN VITRO Miia Turpeinen, Riina Nieminen, Tarja Juntunen, Drug Metabolism and Disposition	2004	107
Pharmacogenetic Explanation for Excessive β-Blockade Following Timolol Eye Drops Tim I. Edeki JAMA	1995	93
PHYSIOLOGICAL DISPOSITION AND METABOLISM OF TIMOLOL IN MAN AND LABORATORY ANIMALS Dominick J. Tocco, A E Duncan, F A deLuna, Drug Metabolism and Disposition	1975	91

Page 1