Timolol Metabolism in Human Liver Microsomes Is Mediated Principally by CYP2D6

CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants

L M Hesse, Karthik Venkatakrishnan, Michael H. Court et al. · Drug Metabolism and Disposition · 2000 · 399 citations

Medicine, Biochemistry, Pharmacology +17

Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity

Stephanie Faucette, Roy L. Hawke, Edward L. LeCluyse et al. · Drug Metabolism and Disposition · 2000 · 356 citations

Medicine, Biochemistry, Pharmacology +17

Amodiaquine Clearance and Its Metabolism to N-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate

Xueqing Li, Anders Björkman, Tommy B. Andersson et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 285 citations

Medicine, Pharmacokinetics, Pharmacology +17

Adverse Reactions from Timolol Administration

E. Michael Van Buskirk · Ophthalmology · 1980 · 283 citations

Pharmacy, Pharmacology, Pharmacotherapy +13

Stereoselective Metabolism of Omeprazole by Human Cytochrome P450 Enzymes

Angela Äbelö, Tommy B. Andersson, Madeleine Antonsson et al. · Drug Metabolism and Disposition · 2000 · 276 citations

Medicine, Pharmacokinetics, Pharmacology +17