Concepedia

Edaravone (3-Methyl-1-phenyl-2-pyrazolin-5-one), a Radical Scavenger, Prevents 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Neurotoxicity in the Substantia Nigra but Not the Striatum

Toshiyuki Kawasaki, Kotaro Ishihara, Yukio Ago, Toshio Matsuda

Journal of Pharmacology and Experimental Therapeutics · 2007 · 38 citations · 35 references

DOI

Concepts

References

35

Mitochondrial Complex I Deficiency in Parkinson's Disease

Anthony H.V. Schapira, Jonathan M. Cooper, David T. Dexter et al. · Journal of Neurochemistry · 1990 · 2.3K citations

, , +13

Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Du Chu Wu, Vernice Jackson‐Lewis, Miquel Vila et al. · Journal of Neuroscience · 2002 · 1.2K citations · Full text

, , +17

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

Gabriel T. Liberatore, Vernice Jackson‐Lewis, Slobodanka Vukosavić et al. · Nature Medicine · 1999 · 1K citations

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.

Serge Przedborski, Vernice Jackson‐Lewis, R Yokoyama et al. · Proceedings of the National Academy of Sciences · 1996 · 629 citations

, , +17

Time course of nigrostriatal degeneration in parkinson's disease

Peter Riederer, St. Wuketich · Journal of Neural Transmission · 1976 · 568 citations

, , +14